Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 5/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | CDK7 | P50613 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31321937 | 0.92 | PLA2G2A (0.40) | RXRARXRBRXRGPLA2G2APIK3CD | |
| SCHEMBL31269035 | 0.92 | CNR1 (0.36) | S1PR5KMT2AFFAR4FFAR1HTR6 | |
| SCHEMBL31269288 | 0.92 | PLA2G2A (0.36) | S1PR1GAATHRATHRBRXRA | |
| SCHEMBL31268989 | 0.91 | S1PR1 (0.40) | S1PR1S1PR5PDGFRAPIM1PRKD3 | |
| SCHEMBL31268742 | 0.91 | S1PR1 (0.40) | S1PR1S1PR5PDGFRAPIM1PRKD3 | |
| SCHEMBL31269340 | 0.89 | S1PR1 (0.36) | S1PR1S1PR5PDGFRAKDM4EALDH1A1 | |
| SCHEMBL30983523 | 0.88 | PLA2G2A (0.38) | FFAR4PLA2G2APIK3CDPTGDR2 | |
| SCHEMBL31268992 | 0.88 | CNR1 (0.35) | S1PR5KMT2AFFAR4FFAR1HTR6 | |
| SCHEMBL30983451 | 0.87 | PLA2G2A (0.38) | PLA2G2AALOX5APPIK3CDPTGDR2 | |
| SCHEMBL31268807 | 0.87 | S1PR1 (0.36) | S1PR1S1PR5PDGFRAPIM1PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |