SCHEMBL31269203

SCHEMBL31269203

CC1(Oc2ncnc3c2nc(-c2ccc(CC(N)=O)cc2Cl)n3Cc2nnc(C3CC3)s2)CC1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ PIK3CD O00329 3/20 0.36
▸ CNR1 P21554 2/20 0.32
▸ CNR2 P34972 2/20 0.32
▸ DGAT1 O75907 1/20 0.32
▸ ROCK2 O75116 1/20 0.30
▸ PTGDR2 Q9Y5Y4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31269311 0.91 PIK3CD (0.35) PIK3CDCNR1CNR2DGAT1
SCHEMBL31268828 0.88 PIK3CD (0.38) PIK3CDCNR1CNR2DGAT1
SCHEMBL31269353 0.86 DGAT1 (0.35) PIK3CDCNR1CNR2DGAT1
SCHEMBL31269283 0.86 PIK3CD (0.38) PIK3CDCNR1CNR2DGAT1
SCHEMBL31268794 0.85 PIK3CD (0.36) PIK3CDCNR1CNR2DGAT1
SCHEMBL31269290 0.84 PIK3CD (0.37) PIK3CDCNR1CNR2DGAT1ROCK2
SCHEMBL31268788 0.84 PIK3CD (0.37) PIK3CDCNR1CNR2DGAT1
SCHEMBL31269497 0.83 PIK3CD (0.35) PIK3CDCNR1CNR2DGAT1
SCHEMBL31268988 0.83 PIK3CD (0.36) PIK3CDCNR1CNR2DGAT1
SCHEMBL31269255 0.83 PDE10A (0.38) PIK3CDCNR1DGAT1PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4689155-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS Astrazeneca AB (SE) 2026-02-11 — — EP disclosed
WO-2024201368-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS ASTRAZENECA AB (SE) 2024-10-03 — — WO disclosed
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