Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 6/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30983383 | 0.95 | PDE2A (0.44) | PDE2AKDM4EALDH1A1LTA4HDRD2 | |
| SCHEMBL30983473 | 0.89 | PDE2A (0.43) | PDE2AKDM4EALDH1A1DRD2NPY1R | |
| SCHEMBL31269344 | 0.88 | PDE2A (0.45) | HTR6PDE2AKDM4EALDH1A1LTA4H | |
| SCHEMBL30983970 | 0.88 | PDE2A (0.42) | HTR6PDE2AKDM4EALDH1A1DRD2 | |
| SCHEMBL31269150 | 0.85 | PLA2G2A (0.38) | — | |
| SCHEMBL30983378 | 0.85 | HTR6 (0.41) | HTR6PDE2AKDM4EALDH1A1LTA4H | |
| SCHEMBL30983477 | 0.84 | PDE2A (0.42) | HTR6PDE2AKDM4EALDH1A1LTA4H | |
| SCHEMBL30984054 | 0.82 | PDE2A (0.42) | HTR6PDE2AKDM4EALDH1A1LTA4H | |
| SCHEMBL30984056 | 0.82 | PDE2A (0.42) | HTR6PDE2AKDM4EALDH1A1LTA4H | |
| SCHEMBL30983795 | 0.79 | PDE2A (0.42) | HTR6PDE2AKDM4EALDH1A1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |