Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 2/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31268792 | 0.96 | HRH4 (0.35) | PIK3CDEGFRCNR1KCNH2HRH4 | |
| SCHEMBL30983550 | 0.94 | PDK2 (0.37) | DRD2PIK3CDEGFRCNR1KCNH2 | |
| SCHEMBL30983862 | 0.94 | KCNH2 (0.33) | DRD2PIK3CDMEN1KMT2AKCNH2 | |
| SCHEMBL31269042 | 0.92 | DRD2 (0.38) | DRD2PIK3CDMEN1KMT2A | |
| SCHEMBL30983578 | 0.92 | DRD2 (0.34) | DRD2PIK3CDCNR1KCNH2HRH4 | |
| SCHEMBL31269246 | 0.91 | HRH3 (0.35) | PIK3CDHRH4 | |
| SCHEMBL31269010 | 0.91 | HRH3 (0.35) | PIK3CDHRH4 | |
| SCHEMBL31268971 | 0.91 | PIK3CD (0.31) | PIK3CDMEN1KMT2A | |
| SCHEMBL31269258 | 0.91 | HRH4 (0.36) | PIK3CDKCNH2HRH4 | |
| SCHEMBL30983439 | 0.89 | PIK3CD (0.39) | DRD2PIK3CDMEN1KMT2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |