Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31270194 | 0.92 | GPR119 (0.44) | GPR119PLA2G7CHEK2 | |
| SCHEMBL31270202 | 0.87 | GPR119 (0.50) | GPR119CHEK2 | |
| SCHEMBL31270113 | 0.85 | SLC5A1 (0.43) | GPR119CHEK2 | |
| SCHEMBL30283471 | 0.85 | GPR119 (0.47) | GPR119CHEK2 | |
| SCHEMBL29269437 | 0.85 | GPR119 (0.47) | GPR119CHEK2 | |
| SCHEMBL31270048 | 0.84 | GPR119 (0.41) | GPR119CHEK2 | |
| SCHEMBL31270052 | 0.81 | GPR119 (0.40) | GPR119PLA2G7 | |
| SCHEMBL31694949 | 0.81 | PLA2G7 (0.41) | GPR119PLA2G7CHEK2 | |
| SCHEMBL31269965 | 0.80 | GPR119 (0.46) | GPR119CHEK2 | |
| SCHEMBL31269860 | 0.80 | RET (0.41) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240415819-A1 | MACROCYCLIC COMPOUNDS AS PROTEASOME SUBUNIT BETA TYPE-5 INHIBITORS | QLi5 Therapeutics AG (DE) | 2024-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240415819-A1 | MACROCYCLIC COMPOUNDS AS PROTEASOME SUBUNIT BETA TYPE-5 INHIBITORS | PSMB5, PSMA5, PSMB1 | GPR119 4139/4885PLA2G7 1499/4885CHEK2 3816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.