Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31271122 | 0.78 | SIGMAR1 (0.48) | SIGMAR1OPRM1DRD2OPRL1MGLL | |
| SCHEMBL1966477 | 0.77 | SIGMAR1 (0.61) | SIGMAR1OPRM1DRD2OPRL1POLB | |
| SCHEMBL6825469 | 0.75 | SIGMAR1 (0.68) | SIGMAR1OPRM1DRD2CYP3A4HSD17B10 | |
| SCHEMBL31271017 | 0.75 | CYP2D6 (0.46) | SIGMAR1OPRM1OPRL1MGLLCHRM2 | |
| SCHEMBL7952645 | 0.74 | SIGMAR1 (0.59) | SIGMAR1OPRM1DRD2OPRL1CYP3A4 | |
| SCHEMBL1975664 | 0.73 | SLC6A2 (0.60) | SIGMAR1OPRM1OPRL1CYP3A4HSD17B10 | |
| SCHEMBL14027000 | 0.73 | ALDH1A1 (0.64) | SIGMAR1DRD2OPRL1POLBCYP3A4 | |
| SCHEMBL17611770 | 0.73 | CHRM2 (0.69) | SIGMAR1OPRM1MGLLCHRM2CHRM3 | |
| SCHEMBL11686136 | 0.72 | SIGMAR1 (0.68) | SIGMAR1OPRM1OPRL1POLBCYP3A4 | |
| SCHEMBL6777379 | 0.72 | SIGMAR1 (0.60) | SIGMAR1DRD2OPRL1POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4719384-A2 | COMPOUNDS WITH ANTIFUNGAL PROPERTIES | Trustees of Dartmouth College (US) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024249290-A2 | COMPOUNDS WITH ANTIFUNGAL PROPERTIES | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2024-12-05 | — | — | WO | disclosed |