SCHEMBL31271017

SCHEMBL31271017

COC(=O)/C=C1/CCOC2(CCN(Cc3ccccc3)CC2)C1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 4/20 0.46
MGLL Q99685 2/20 0.45
CHRM2 P08172 2/20 0.44
CHRM3 P20309 2/20 0.44
SIGMAR1 Q99720 5/20 0.43
ALDH1A1 P00352 1/20 0.42
OPRL1 P41146 1/20 0.41
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41
TSHR P16473 1/20 0.41
OPRM1 P35372 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31271122 0.80 SIGMAR1 (0.48) CYP2D6MGLLCHRM2CHRM3SIGMAR1
SCHEMBL5036890 0.79 KMT2A (0.48) CYP2D6SIGMAR1ALDH1A1HDAC4HDAC1
SCHEMBL24489551 0.76 PRKCA (0.34)
SCHEMBL31270584 0.75 SIGMAR1 (0.54) CYP2D6MGLLCHRM2CHRM3SIGMAR1
SCHEMBL29560686 0.74 OPRK1 (0.47) ALDH1A1
SCHEMBL12606489 0.74 OPRK1 (0.47) ALDH1A1
SCHEMBL3498095 0.72 CYP2D6 (0.56) CYP2D6CHRM2CHRM3ALDH1A1OPRL1
SCHEMBL17714551 0.69 CYP2D6 (0.55) CYP2D6CHRM2CHRM3ALDH1A1OPRL1
SCHEMBL17611770 0.69 CHRM2 (0.69) CYP2D6MGLLCHRM2CHRM3SIGMAR1
SCHEMBL18280972 0.68 CYP2D6 (0.46) CYP2D6ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4719384-A2 COMPOUNDS WITH ANTIFUNGAL PROPERTIES Trustees of Dartmouth College (US) 2026-04-08 EP disclosed
WO-2024249290-A2 COMPOUNDS WITH ANTIFUNGAL PROPERTIES TRUSTEES OF DARTMOUTH COLLEGE (US) 2024-12-05 WO disclosed