Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 6/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680911 | 0.84 | AR (0.46) | ARALDH1A1KDM4EALOX12CASP1 | |
| SCHEMBL1432800 | 0.77 | ALDH1A1 (0.55) | ARALDH1A1KDM4EALOX12CASP1 | |
| SCHEMBL10332004 | 0.77 | AR (0.53) | ARALDH1A1KDM4EALOX12CASP1 | |
| SCHEMBL1701348 | 0.73 | PIK3CD (0.51) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL26990021 | 0.72 | HPGD (0.51) | ARALDH1A1KDM4EALOX12CASP1 | |
| SCHEMBL3121814 | 0.72 | PRKDC (0.43) | ARALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL3127062 | 0.71 | AR (0.50) | ARALDH1A1KDM4EALOX12CASP1 | |
| SCHEMBL28725597 | 0.70 | MAPT (0.55) | ARALDH1A1KDM4EALOX12CASP1 | |
| SCHEMBL7860579 | 0.69 | AR (0.56) | ARALDH1A1KDM4EALOX12CASP1 | |
| SCHEMBL3121764 | 0.67 | ALDH1A1 (0.57) | ALDH1A1KDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001126-A1 | THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2010-01-07 | — | — | WO | disclosed |