Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | UBE2N | P61088 | 3/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RUVBL1 | Q9Y265 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31270687 | 0.90 | PPARG (0.54) | PPARGNISCHACHEUBE2NPAX8 | |
| SCHEMBL15788315 | 0.88 | PPARG (0.61) | PPARGNISCHACHEUBE2NPAX8 | |
| SCHEMBL31270763 | 0.81 | NISCH (0.60) | PPARGNISCHACHEUBE2NPAX8 | |
| SCHEMBL25602980 | 0.80 | RUVBL1 (0.55) | PPARGNISCHACHEUBE2NPAX8 | |
| Formic Acid SCHEMBL31271011 | 0.77 | PPARG (0.58) | PPARGNISCHACHEUBE2NPAX8 | |
| SCHEMBL17086964 | 0.76 | ACHE (0.82) | PPARGNISCHACHEUBE2NPAX8 | |
| SCHEMBL25607127 | 0.76 | POLB (0.70) | PPARGNISCHACHEUBE2NLMNA | |
| SCHEMBL31270741 | 0.76 | NISCH (0.52) | PPARGNISCHACHEUBE2NPAX8 | |
| SCHEMBL31270776 | 0.76 | NISCH (0.55) | PPARGNISCHACHEUBE2NPAX8 | |
| SCHEMBL25606799 | 0.75 | ACHE (0.70) | PPARGNISCHACHEUBE2NPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220676-A1 | MRNA DEGRADERS AND METHODS OF USE THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-10-24 | — | — | WO | disclosed |