SCHEMBL31270774

SCHEMBL31270774

CC(C)(C)OC(=O)N1CCN(CCOc2ccc(C=O)cc2O)CC1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ RXFP1 Q9HBX9 1/20 0.45
▸ GPR4 P46093 1/20 0.43
▸ EPHX2 P34913 7/20 0.43
▸ ALDH1A1 P00352 1/20 0.41
▸ AOX1 Q06278 1/20 0.41
▸ ACKR3 P25106 1/20 0.41
▸ CHRM2 P08172 1/20 0.40
▸ CHRM4 P08173 1/20 0.40
▸ CHRM1 P11229 1/20 0.40
▸ CHRM3 P20309 1/20 0.40
▸ ABCB1 P08183 1/20 0.40
▸ TERT O14746 1/20 0.39
▸ SQOR Q9Y6N5 1/20 0.39
▸ POLB P06746 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ HTR1B P28222 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3423418 0.83 EPHX2 (0.47) EPHX2ALDH1A1ACKR3POLBKDM4E
SCHEMBL1673377 0.83 GPR4 (0.53) GPR4EPHX2
SCHEMBL31270890 0.82 DRD2 (0.44) —
SCHEMBL3564150 0.80 ALDH1A1 (0.49) ALDH1A1AOX1KDM4E
SCHEMBL31269095 0.79 RXFP1 (0.45) RXFP1GPR4EPHX2ALDH1A1ACKR3
SCHEMBL30984002 0.79 POLB (0.43) RXFP1GPR4EPHX2ALDH1A1ACKR3
SCHEMBL5692306 0.78 ALDH1A1 (0.51) ALDH1A1AOX1POLBKDM4E
SCHEMBL1555415 0.78 EPHX2 (0.57) EPHX2
SCHEMBL18021941 0.78 VEGFA (0.48) ALDH1A1CHRM2CHRM4CHRM1CHRM3
SCHEMBL31271107 0.77 KDM4E (0.47) ALDH1A1AOX1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024220676-A1 MRNA DEGRADERS AND METHODS OF USE THEREOF UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-10-24 — — WO disclosed
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