Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 3/20 | 0.32 |
| ▸ | PGR | P06401 | 2/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2123551 | 0.86 | IMPDH2 (0.36) | IMPDH2ARPGRDYRK1AEGFR | |
| SCHEMBL19631216 | 0.85 | IMPDH2 (0.40) | IMPDH2ARPGRALDH1A1L3MBTL1 | |
| SCHEMBL25606042 | 0.80 | IMPDH2 (0.37) | IMPDH2ARPGRALDH1A1L3MBTL1 | |
| SCHEMBL31589251 | 0.79 | F2RL1 (0.39) | IMPDH2ARPGRALDH1A1LMNA | |
| SCHEMBL31575236 | 0.75 | KDM4E (0.35) | IMPDH2AREGFRALDH1A1LMNA | |
| SCHEMBL20604884 | 0.74 | IMPDH2 (0.46) | IMPDH2ARDYRK1AALDH1A1L3MBTL1 | |
| SCHEMBL30219113 | 0.73 | KDM4E (0.33) | ALDH1A1MAPT | |
| SCHEMBL18879668 | 0.73 | IMPDH2 (0.37) | IMPDH2ARPGRALDH1A1L3MBTL1 | |
| SCHEMBL19431454 | 0.72 | XDH (0.36) | IMPDH2ARPGRALDH1A1XDH | |
| SCHEMBL2121819 | 0.70 | CA1 (0.42) | ALDH1A1L3MBTL1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727939-A1 | 5-(CINNOLIN-6-YL)THIAZOLE COMPOUNDS FOR TREATING NEUROLOGICAL DISORDERS | Prothena Biosciences Limited (IE) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024259116-A1 | 5-(CINNOLIN-6-YL)THIAZOLE COMPOUNDS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2024-12-19 | — | — | WO | disclosed |