SCHEMBL31271978

SCHEMBL31271978

CCCCCCCCCCN(CCCCCCCCCC)C(=O)CCCCCCCN(CCCCCCCC(=O)N(CCCCCCCCCC)CCCCCCCCCC)C(=O)C(F)CCN(C)C

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 5/20 0.40
KDM4C Q9H3R0 7/20 0.40
KDM5A P29375 4/20 0.40
PHF8 Q9UPP1 2/20 0.40
CES2 O00748 1/20 0.39
MAPT P10636 1/20 0.38
EPHX2 P34913 2/20 0.38
KDM5C P41229 1/20 0.38
KDM5B Q9UGL1 1/20 0.38
KDM4A O75164 5/20 0.37
KDM7A Q6ZMT4 1/20 0.37
KDM2A Q9Y2K7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31271923 1.00 DNM1 (0.40) DNM1KDM4CKDM5APHF8CES2
SCHEMBL31271866 0.86 CES2 (0.39) KDM4CKDM5APHF8CES2MAPT
SCHEMBL31272298 0.86 CES2 (0.39) KDM4CKDM5APHF8CES2MAPT
SCHEMBL26486042 0.82 DNM1 (0.58) DNM1KDM4CKDM5APHF8EPHX2
SCHEMBL31271676 0.81 MAPT (0.38) DNM1KDM4CKDM5APHF8MAPT
SCHEMBL8483319 0.78 DNM1 (0.54) DNM1KDM4CKDM5APHF8KDM4A
SCHEMBL13571403 0.78 DNM1 (0.54) DNM1KDM4CKDM5APHF8KDM4A
SCHEMBL25129667 0.78 CES2 (0.52) KDM4CKDM5APHF8CES2
SCHEMBL25129665 0.78 CES2 (0.52) KDM4CKDM5APHF8CES2
SCHEMBL9694578 0.78 CES2 (0.52) KDM4CKDM5APHF8CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727915-A1 AMIDE CONTAINING LIPIDS Acuitas Therapeutics, Inc. (CA) 2026-04-22 EP disclosed
US-20240423914-A1 AMIDE CONTAINING LIPIDS Acuitas Therapeutics, Inc. (CA) 2024-12-26 US disclosed
WO-2024259315-A1 AMIDE CONTAINING LIPIDS Acuitas Therapeutics, Inc. (CA) 2024-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240423914-A1 AMIDE CONTAINING LIPIDS PHOSPHO1, SGMS1, SGMS2 DNM1 604/4885KDM4C 3921/4885KDM5A 4569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.