Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 9/20 | 0.38 |
| ▸ | DDO | Q99489 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31273131 | 0.84 | DAO (0.51) | DAOMAPTCNR2KDM4ETSHR | |
| SCHEMBL31423270 | 0.83 | ALDH1A1 (0.52) | DAONPC1MAPTKDM4ETSHR | |
| SCHEMBL31273200 | 0.82 | DAO (0.55) | DAOSMN1; SMN2DDOKDM4ETSHR | |
| SCHEMBL31272773 | 0.80 | DAO (0.51) | DAOCNR2KDM4ETSHRHSD17B10 | |
| SCHEMBL31273602 | 0.79 | DAO (0.39) | DAODDOKDM4EHSD17B10MEN1 | |
| SCHEMBL31273285 | 0.79 | EIF4A3 (0.48) | DAOMAPTDDOKDM4ETSHR | |
| SCHEMBL31273400 | 0.79 | DAO (0.39) | DAOSMN1; SMN2DDOKDM4ETSHR | |
| SCHEMBL31272756 | 0.78 | DAO (0.38) | DAODDOKDM4ETSHRHSD17B10 | |
| SCHEMBL31423379 | 0.78 | KDM4E (0.39) | DAOSMN1; SMN2DDOKDM4ETSHR | |
| SCHEMBL31423310 | 0.75 | DAO (0.62) | DAOMAPTCNR2KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |
| CN-119101045-A | Nitrogen-containing heterocyclic compounds, and preparation method and application thereof | 上海宇道生物技术有限公司 | 2024-12-10 | — | — | CN | disclosed |