Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31273131 | 0.85 | DAO (0.51) | DAOKDM4EGAAALDH1A1POLB | |
| SCHEMBL31423270 | 0.84 | ALDH1A1 (0.52) | DAOKDM4EGAAALDH1A1POLB | |
| SCHEMBL31273184 | 0.80 | DAO (0.49) | DAOKDM4EALDH1A1CNR2HSD17B10 | |
| SCHEMBL10330642 | 0.77 | DAO (0.63) | DAOKDM4EGAAALDH1A1POLB | |
| SCHEMBL31222324 | 0.77 | KDM4E (0.61) | DAOKDM4EGAAALDH1A1POLB | |
| SCHEMBL25427065 | 0.76 | ALDH1A1 (0.56) | DAOKDM4EGAAALDH1A1POLB | |
| SCHEMBL30529281 | 0.76 | ALDH1A1 (0.56) | DAOKDM4EGAAALDH1A1POLB | |
| SCHEMBL29415463 | 0.75 | CASP3 (0.55) | KDM4EGAAALDH1A1POLBGRIK1 | |
| SCHEMBL2807085 | 0.75 | CASP3 (0.55) | KDM4EGAAALDH1A1POLBGRIK1 | |
| SCHEMBL27840670 | 0.75 | KDM4E (0.51) | DAOKDM4EGAAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |
| CN-119101045-A | Nitrogen-containing heterocyclic compounds, and preparation method and application thereof | 上海宇道生物技术有限公司 | 2024-12-10 | — | — | CN | disclosed |