Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 2/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | PTPRB | P23467 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25438024 | 0.71 | PABPC1 (0.38) | RAB9ANPC1MAPTCA12CA1 | |
| Bromide SCHEMBL18063231 | 0.68 | CA1 (0.41) | CA12CA1KMT2A | |
| Ethoxycarbonyl Group SCHEMBL28110990 | 0.67 | CTSK (0.37) | RAB9ANPC1MAPTCA12CA1 | |
| Ethoxycarbonyl Group SCHEMBL27830700 | 0.66 | GAA (0.46) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| Ethoxycarbonyl Group SCHEMBL27838433 | 0.65 | NAMPT (0.63) | RAB9ANPC1MAPTKDM4EKMT2A | |
| SCHEMBL29488493 | 0.65 | HDAC3 (0.54) | RAB9ANPC1MAPTCA12CA1 | |
| SCHEMBL694391 | 0.65 | HDAC3 (0.54) | RAB9ANPC1MAPTCA12CA1 | |
| Ethoxycarbonyl Group SCHEMBL31274185 | 0.64 | NAMPT (0.38) | RAB9ANPC1MAPTKDM4EMIF | |
| Ethoxycarbonyl Group SCHEMBL28145185 | 0.64 | BTK (0.55) | CA1HDAC1HDAC6KMT2A | |
| Ethoxycarbonyl Group SCHEMBL3552678 | 0.63 | GAA (0.39) | ALDH1A1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867535-B | Substituted benzamides as modulators of TREX1 | 星座制药公司 | 2024-12-17 | — | — | CN | disclosed |