SCHEMBL3127929

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3121101	0.81	PNMT (0.60)	PNMTOPRM1OPRL1CXCR4PRCP
	SCHEMBL3129918	0.81	PNMT (0.60)	PNMTOPRM1OPRL1KCNH2CXCR4
	SCHEMBL3124084	0.77	PNMT (0.56)	PNMTOPRM1OPRL1KCNH2CHRM2
	SCHEMBL172636	0.77	PNMT (0.69)	PNMTOPRM1OPRL1KCNH2PRCP
	SCHEMBL13453377	0.77	PNMT (0.69)	PNMTOPRM1OPRL1KCNH2PRCP
	SCHEMBL14355729	0.77	PNMT (0.69)	PNMTOPRM1OPRL1KCNH2PRCP
	SCHEMBL3124097	0.76	PNMT (0.62)	PNMTPRCP
	SCHEMBL8853548	0.75	PNMT (0.71)	PNMTOPRM1OPRL1PRCPADRA2A
	SCHEMBL8853554	0.75	PNMT (0.71)	PNMTOPRM1OPRL1PRCPADRA2A
	SCHEMBL14997331	0.74	PNMT (0.56)	PNMTPRCPADRA2AADRA2BADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.