SCHEMBL31279744

SCHEMBL31279744

O=C1CCN(N2C(=O)c3ccc(CN4CC=C(c5ccoc5)CC4)cc3C2=O)C(=O)N1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 5/20 0.42
IKZF1 Q13422 2/20 0.40
DRD2 P14416 1/20 0.40
DRD4 P21917 1/20 0.40
IKZF2 Q9UKS7 1/20 0.35
HTR1A P08908 3/20 0.34
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CDK4 P11802 1/20 0.33
CCND1 P24385 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31279366 0.86 IKZF1 (0.46) PARP1IKZF1DRD2DRD4IKZF2
SCHEMBL31278570 0.84 PARP1 (0.39) PARP1IKZF1DRD2DRD4IKZF2
SCHEMBL31279432 0.84 PARP1 (0.41) PARP1IKZF1DRD2DRD4IKZF2
SCHEMBL31279714 0.82 PARP1 (0.40) PARP1IKZF1DRD2DRD4IKZF2
SCHEMBL31338073 0.81 IKZF1 (0.55) PARP1IKZF1IKZF2
SCHEMBL31279643 0.81 PARP1 (0.47) PARP1IKZF1DRD2DRD4IKZF2
SCHEMBL31279867 0.80 SIGMAR1 (0.41) PARP1IKZF1DRD2DRD4IKZF2
SCHEMBL31279354 0.80 CCNT1 (0.39) PARP1IKZF1IKZF2
SCHEMBL31278810 0.79 IKZF1 (0.38) PARP1IKZF1DRD2DRD4IKZF2
SCHEMBL31279209 0.79 DRD2 (0.41) PARP1IKZF1DRD2DRD4IKZF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4722207-A1 OXOISOINDOLINYL-SUBSTITUTED TETRAHYDROPYRIMIDINEDIONE DERIVATIVE AND USE THEREOF Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) 2026-04-08 EP claimed
CN-119451952-A Oxo-isoindolinyl substituted tetrahydropyrimidinedione derivative and application thereof 标新生物医药科技(上海)有限公司 2025-02-14 CN claimed
WO-2024245444-A1 OXOISOINDOLINYL-SUBSTITUTED TETRAHYDROPYRIMIDINEDIONE DERIVATIVE AND USE THEREOF 标新生物医药科技(上海)有限公司 2024-12-05 WO claimed
EP-4722207-A1 OXOISOINDOLINYL-SUBSTITUTED TETRAHYDROPYRIMIDINEDIONE DERIVATIVE AND USE THEREOF Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) 2026-04-08 EP disclosed
CN-119451952-A Oxo-isoindolinyl substituted tetrahydropyrimidinedione derivative and application thereof 标新生物医药科技(上海)有限公司 2025-02-14 CN disclosed
WO-2024245444-A1 OXOISOINDOLINYL-SUBSTITUTED TETRAHYDROPYRIMIDINEDIONE DERIVATIVE AND USE THEREOF 标新生物医药科技(上海)有限公司 2024-12-05 WO disclosed