Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 9/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23663678 | 1.00 | KDM4E (0.42) | KDM4EPOLBMAPTKMT2ATNF | |
| SCHEMBL28922385 | 0.84 | NOTUM (0.50) | KDM4EKMT2AHPGDNOTUMALDH1A1 | |
| SCHEMBL31280881 | 0.75 | NUDT1 (0.56) | KDM4EPOLBMAPTKMT2AHPGD | |
| SCHEMBL23663615 | 0.75 | NUDT1 (0.56) | KDM4EPOLBMAPTKMT2AHPGD | |
| SCHEMBL19297838 | 0.74 | KDM4E (0.40) | KDM4EPOLBMAPTKMT2ATNF | |
| SCHEMBL27132794 | 0.74 | KMT2A (0.45) | KDM4EPOLBMAPTKMT2AHPGD | |
| SCHEMBL21919495 | 0.72 | KDM4E (0.42) | KDM4EPOLBMAPTKMT2AHPGD | |
| SCHEMBL22303058 | 0.71 | ALDH1A1 (0.42) | KDM4EPOLBMAPTKMT2ATNF | |
| SCHEMBL29340344 | 0.69 | ALDH1A1 (0.51) | KDM4EPOLBMAPTKMT2AHPGD | |
| SCHEMBL2123060 | 0.68 | MGAM (0.46) | TNFLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114981268-B | Pyrimidine-4 (3H) -ketone heterocyclic compound, preparation method and application thereof in medicine | 北京诺诚健华医药科技有限公司 | 2025-01-28 | — | — | CN | disclosed |