Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31284165 | 0.89 | NOTUM (0.47) | MAPTNOTUMSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL31283914 | 0.89 | SIRT6 (0.41) | SIRT6MAPTNOTUMSMN1; SMN2ALDH1A1 | |
| SCHEMBL31284595 | 0.87 | NOTUM (0.46) | MAPTNOTUMSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL31285341 | 0.86 | NOTUM (0.46) | MAPTNOTUMSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL31285385 | 0.86 | NOTUM (0.46) | MAPTNOTUMSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL31284457 | 0.85 | NOTUM (0.45) | MAPTNOTUMSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL31285325 | 0.85 | NOTUM (0.45) | MAPTNOTUMSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL31284447 | 0.85 | NOTUM (0.45) | MAPTNOTUMSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL31283935 | 0.84 | NOTUM (0.44) | MAPTNOTUMSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL31285035 | 0.81 | NOTUM (0.46) | MAPTNOTUMSMN1; SMN2RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119176772-A | Compound with Mrgpr X receptor inhibition effect and application thereof | 博济医药科技股份有限公司 | 2024-12-24 | — | — | CN | disclosed |