Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 3/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | FLT1 | P17948 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30946437 | 0.82 | NOTUM (0.48) | NOTUMLRRK2BRD4TRPV1RXRA | |
| SCHEMBL18377889 | 0.78 | NOTUM (0.52) | NOTUMBRD4TRPV1RXRAGRIN1 | |
| SCHEMBL31284304 | 0.72 | NOTUM (0.42) | NOTUMLRRK2BRD4TRPV1STS | |
| SCHEMBL869450 | 0.69 | KDM1A (0.42) | NOTUMHCAR1S1PR4 | |
| SCHEMBL29426988 | 0.69 | KDM1A (0.42) | NOTUMHCAR1S1PR4 | |
| SCHEMBL30946497 | 0.68 | HCAR1 (0.37) | NOTUMHCAR1 | |
| SCHEMBL20349815 | 0.68 | NOTUM (0.48) | NOTUMLRRK2BRD4RXRAGRIN1 | |
| SCHEMBL21263902 | 0.65 | NOTUM (0.59) | NOTUMRXRAGRIN1GRIN2BAR | |
| SCHEMBL12684833 | 0.65 | NOTUM (0.51) | NOTUMAR | |
| SCHEMBL21792175 | 0.65 | NOTUM (1.00) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743085-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Tenvie Therapeutics, Inc. (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025019357-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | NICO THERAPEUTICS, INC. (US) | 2025-01-23 | — | — | WO | disclosed |