Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 2/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | STS | P08842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18377889 | 0.74 | NOTUM (0.52) | NOTUMBRD4APPTRPV1RBP4 | |
| SCHEMBL30946437 | 0.72 | NOTUM (0.48) | NOTUMBRD4APPTRPV1PDE10A | |
| SCHEMBL31284267 | 0.72 | NOTUM (0.48) | NOTUMBRD4APPTRPV1PDE10A | |
| SCHEMBL30946402 | 0.71 | ESR1 (0.34) | ESR1ESR2NTRK1 | |
| SCHEMBL31284601 | 0.71 | NOTUM (0.38) | NOTUMESR1ESR2 | |
| SCHEMBL6135928 | 0.70 | ESR1 (0.44) | ESR1ESR2 | |
| SCHEMBL16339338 | 0.68 | GRM5 (0.36) | ESR1ESR2RBP4 | |
| SCHEMBL8586278 | 0.67 | MAPT (0.50) | ESR1ESR2 | |
| SCHEMBL30402030 | 0.66 | ESR1 (0.40) | NOTUMESR1ESR2 | |
| SCHEMBL31231692 | 0.66 | KMO (0.36) | NOTUMESR1ESR2NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743085-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Tenvie Therapeutics, Inc. (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025019357-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | NICO THERAPEUTICS, INC. (US) | 2025-01-23 | — | — | WO | disclosed |