Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14595477 | 0.78 | KMT2A (0.51) | KMT2AMEN1POLBGAAALDH1A1 | |
| SCHEMBL10591725 | 0.78 | KMT2A (0.65) | KMT2AMEN1POLBGAAALDH1A1 | |
| SCHEMBL6695378 | 0.75 | KMT2A (0.53) | KMT2AMEN1POLBGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL8129113 | 0.74 | KMT2A (0.51) | KMT2AMEN1POLBGAAALDH1A1 | |
| SCHEMBL14868617 | 0.74 | ALDH1A1 (0.48) | KMT2AMEN1POLBGAAALDH1A1 | |
| SCHEMBL10310225 | 0.74 | KMT2A (0.59) | KMT2AMEN1POLBGAAALDH1A1 | |
| SCHEMBL18415483 | 0.73 | POLB (0.77) | KMT2AMEN1POLBALDH1A1EPHX2 | |
| SCHEMBL8894996 | 0.73 | MCL1 (0.50) | KMT2AMEN1POLBGAAALDH1A1 | |
| SCHEMBL13584238 | 0.72 | ALDH1A1 (0.46) | KMT2AMEN1POLBGAAALDH1A1 | |
| SCHEMBL28057334 | 0.72 | ALDH1A1 (0.52) | KMT2AMEN1POLBGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747228-A1 | INHIBITORS OF PTPMT1 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025019794-A1 | INHIBITORS OF PTPMT1 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-01-23 | — | — | WO | disclosed |