Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.52 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10591725 | 0.76 | KMT2A (0.65) | ALDH1A1POLBL3MBTL1LMNATDP1 | |
| SCHEMBL14595477 | 0.76 | KMT2A (0.51) | ALDH1A1POLBL3MBTL1LMNATDP1 | |
| SCHEMBL1817029 | 0.74 | ALDH1A1 (0.45) | ALDH1A1POLBL3MBTL1LMNAMEN1 | |
| SCHEMBL1455280 | 0.73 | ALDH1A1 (0.64) | ALDH1A1POLBL3MBTL1TDP1HTT | |
| SCHEMBL6695378 | 0.73 | KMT2A (0.53) | ALDH1A1POLBL3MBTL1LMNATDP1 | |
| Hydrochloric Acid SCHEMBL8129113 | 0.72 | KMT2A (0.51) | ALDH1A1POLBL3MBTL1LMNATDP1 | |
| SCHEMBL14868617 | 0.72 | ALDH1A1 (0.48) | ALDH1A1POLBL3MBTL1LMNATDP1 | |
| SCHEMBL31284342 | 0.72 | KMT2A (0.48) | ALDH1A1POLBL3MBTL1LMNATDP1 | |
| SCHEMBL10310225 | 0.72 | KMT2A (0.59) | ALDH1A1POLBL3MBTL1LMNATDP1 | |
| SCHEMBL24575916 | 0.71 | EPHX2 (0.83) | ALDH1A1POLBL3MBTL1TDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105330661-A | N-aryl methyl substituted oxadiazine nitro imine derivative and application thereof | UNIV QINGDAO SCIENCE & TECHNOLOGY | 2016-02-17 | — | — | CN | disclosed |