Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 15/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31284776 | 0.81 | NOTUM (0.43) | NOTUMBCHEP2RX7ALDH1A1NFKB1 | |
| SCHEMBL31284516 | 0.75 | CYP3A4 (0.39) | CYP3A4TSHRALDH1A1POLBNFKB1 | |
| SCHEMBL31285542 | 0.75 | CYP3A4 (0.39) | NOTUMCYP3A4TSHRALDH1A1POLB | |
| SCHEMBL31284181 | 0.74 | TDO2 (0.47) | NOTUMCYP3A4TSHRP2RX7ALDH1A1 | |
| SCHEMBL24168775 | 0.68 | GABRA2 (0.43) | NOTUMCYP3A4ALDH1A1POLBNFKB1 | |
| SCHEMBL30334557 | 0.68 | GABRA2 (0.43) | NOTUMCYP3A4ALDH1A1POLBNFKB1 | |
| SCHEMBL31284697 | 0.68 | CYP3A4 (0.38) | CYP3A4TSHRALDH1A1POLBNFKB1 | |
| SCHEMBL31284750 | 0.68 | TDO2 (0.49) | CYP3A4TSHRALDH1A1POLBNFKB1 | |
| SCHEMBL31284507 | 0.67 | ALDH1A1 (0.46) | NOTUMCYP3A4TSHRALDH1A1POLB | |
| SCHEMBL10914973 | 0.66 | KDM4E (0.50) | CYP3A4TSHRALDH1A1POLBNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743085-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Tenvie Therapeutics, Inc. (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025019357-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | NICO THERAPEUTICS, INC. (US) | 2025-01-23 | — | — | WO | disclosed |