Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 5/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18015330 | 0.83 | PDK2 (0.33) | PDE7A | |
| SCHEMBL34464520 | 0.81 | CYP11B1 (0.38) | LDHAPDE7APARP10PARP11KDM1A | |
| SCHEMBL29036488 | 0.81 | LDHA (0.33) | LDHAPDE7APARP10PARP11KDM1A | |
| SCHEMBL19041482 | 0.78 | LDHA (0.35) | LDHAPDE7APARP10PARP11KDM1A | |
| SCHEMBL9770695 | 0.78 | ALDH1A1 (0.37) | PDE7APARP10PARP11KDM1ATP53 | |
| SCHEMBL5163204 | 0.76 | KDM1A (0.32) | KDM1ATP53CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL9507986 | 0.76 | ALDH1A1 (0.38) | KDM1AGID4TP53CYP1A2ALDH1A1 | |
| SCHEMBL21132394 | 0.76 | PDK2 (0.35) | LDHAPDE7APARP10PARP11KDM1A | |
| SCHEMBL10819305 | 0.76 | HDAC4 (0.37) | PDE7AKDM1A | |
| SCHEMBL29428514 | 0.76 | PDK2 (0.35) | LDHAPDE7APARP10PARP11KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4729516-A1 | SUBSTITUTED IMIDAZOLE DERIVATIVE, INTERMEDIATE, PREPARATION METHOD THEREFOR AND USE THEREOF | Jiangsu NHWA Pharmaceutical Co., Ltd (CN) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024260319-A1 | SUBSTITUTED IMIDAZOLE DERIVATIVE, INTERMEDIATE, PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏恩华药业股份有限公司 | 2024-12-26 | — | — | WO | disclosed |