SCHEMBL9507986

SCHEMBL9507986

CC1(C)CCc2c(N)cccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
HPGD P15428 2/20 0.38
MAPT P10636 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
KMT2A Q03164 1/20 0.38
KDM1A O60341 2/20 0.36
CD44 P16070 2/20 0.35
CYP3A4 P08684 3/20 0.34
TSHR P16473 2/20 0.34
PIK3CA P42336 1/20 0.34
PARP1 P09874 1/20 0.33
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
GID4 Q8IVV7 1/20 0.31
TP53 P04637 1/20 0.31
CYP1A2 P05177 1/20 0.31
MAP2K1 Q02750 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15822259 0.89 KDM1A (0.41) ALDH1A1HPGDMAPTKDM4EMEN1
SCHEMBL24258207 0.87 CES2 (0.38) ALDH1A1HPGDMAPTKDM4EMEN1
Hydrochloric Acid SCHEMBL15532871 0.87 KDM1A (0.40) ALDH1A1HPGDMAPTKDM4EMEN1
SCHEMBL9770695 0.78 ALDH1A1 (0.37) ALDH1A1HPGDMAPTKDM4EMEN1
SCHEMBL24258213 0.78 CD44 (0.36) ALDH1A1HPGDMAPTKDM4EMEN1
SCHEMBL5155072 0.77 LIMK1 (0.34) CD44
SCHEMBL29724586 0.77 LIMK1 (0.34) CD44
SCHEMBL23356013 0.76 CD44 (0.35) ALDH1A1HPGDMAPTKDM4EMEN1
SCHEMBL5163204 0.76 KDM1A (0.32) ALDH1A1MAPTKDM1ACYP3A4TP53
SCHEMBL31284751 0.76 LDHA (0.34) ALDH1A1MAPTKDM1ACYP3A4GID4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62010066-A None JP disclosed
EP-3911309-A1 COMPOSITIONS AND METHODS FOR IMMUNE MODULATION AND TREATMENT OF CANCER Board Of Trustees Of Michigan State University (US) 2021-11-24 EP disclosed
WO-2020150668-A1 COMPOSITIONS AND METHODS FOR IMMUNE MODULATION AND TREATMENT OF CANCER BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2020-07-23 WO disclosed
CN-106795115-A Difluoromethyl nicotine indanyl formamide 拜耳作物科学股份公司 2017-05-31 CN disclosed
EP-0311387-B1 AROMATIC AMINE RESINS, THEIR PRODUCTION PROCESS AND THERMOSETTING RESIN COMPOSITIONS MAKING USE OF THE SAME MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-08-11 EP disclosed
EP-0342943-B1 THERMOSETTING RESIN COMPOSITION MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-08-04 EP disclosed
EP-0256503-B1 PYRIDINECARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDE MITSUBISHI KASEI CORPORATION (JP) 1992-12-02 EP disclosed
US-5145949-A Production process for making aromatic amine resins MITSUI TOATSU CHEMICALS, INC. (JP) 1992-09-08 US disclosed
US-5106953-A Reacting aromatic amines with bishalogenomethyl derivatives; curing agents or raw materials for polyamides MITSUI TOATSU CHEMICALS, INC. (JP) 1992-04-21 US disclosed
EP-0276177-B1 HETEROCYCLIC DERIVATIVES, METHOD FOR THEIR PREPARATION AND FUNGICIDES CONTAINING THEM AS ACTIVE INGREDIENTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-01-29 EP disclosed
US-4837242-A Thiazoles and pyrazoles as fungicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-06-06 US disclosed
EP-0311387-A2 Aromatic amine resins, their production process and thermosetting resin compositions making use of the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-04-12 EP disclosed
EP-0276177-A1 Heterocyclic derivatives, method for their preparation and fungicides containing them as active ingredients SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-07-27 EP disclosed
US-4742074-A Pyrazolecarboxamide derivative and fungicide containing it as active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-05-03 US disclosed
EP-0256503-A2 Pyridinecarboxamide derivatives and their use as fungicide MITSUBISHI KASEI CORPORATION (JP) 1988-02-24 EP disclosed
JP-S6210066-A PYRAZOLECARBOXAMIDE DERIVATIVE AND GERMICIDE CONTAINING SAID DERIVATIVE AS ACTIVE CONSTITUENT SUMITOMO CHEM CO LTD 1987-01-19 JP disclosed
EP-0199822-A1 PYRAZOLECARBOXAMIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND BACTERICIDES CONTAINING THEM AS EFFECTIVE INGREDIENTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-11-05 EP disclosed
EP-0086111-B1 A FUNGICIDAL INDANYLBENZAMIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-10-02 EP disclosed
US-4511581-A Fungicidal indanylbenzamide SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-04-16 US disclosed
EP-0086111-A1 A fungicidal indanylbenzamide SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-08-17 EP disclosed