Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | BCL9 | O00512 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24727719 | 0.83 | ALDH1A1 (0.48) | GAAHTR2ABCL9CTNNB1CYP1A2 | |
| SCHEMBL287764 | 0.81 | GAA (0.54) | GAAHTR2ABCL9CTNNB1KMT2A | |
| SCHEMBL11446812 | 0.80 | CES2 (0.45) | GAABCL9CTNNB1CYP1A2CYP2D6 | |
| SCHEMBL288509 | 0.78 | GAA (0.51) | GAAHTR2ABCL9CTNNB1CYP1A2 | |
| SCHEMBL3373334 | 0.78 | GAA (0.51) | GAAHTR2ABCL9CTNNB1CYP1A2 | |
| SCHEMBL26374 | 0.78 | GAA (0.65) | GAAHTR2ABCL9CTNNB1KMT2A | |
| SCHEMBL14974562 | 0.77 | GAA (0.50) | GAAHTR2ABCL9CTNNB1CYP1A2 | |
| SCHEMBL288139 | 0.76 | BCL9 (0.54) | GAAHTR2ABCL9CTNNB1KMT2A | |
| Hydrochloric Acid SCHEMBL7895043 | 0.76 | GAA (0.62) | GAAHTR2ABCL9CTNNB1KMT2A | |
| SCHEMBL20625250 | 0.76 | GAA (0.51) | GAAHTR2ABCL9CTNNB1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747248-A1 | COMPOUNDS FOR USE IN A METHOD OF TARGETED PROTEIN DEGRADATION | Institute of Cancer Research: Royal Cancer Hospital (The) (GB) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025022093-A1 | COMPOUNDS FOR USE IN A METHOD OF TARGETED PROTEIN DEGRADATION | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2025-01-30 | — | — | WO | disclosed |