Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 9/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.53 |
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11175966 | 1.00 | HSP90AA1 (0.57) | HSP90AA1HTR2ASLC6A4KCNH2LTA4H | |
| SCHEMBL1145316 | 0.86 | SLC6A4 (0.54) | HSP90AA1HTR2ASLC6A4KCNH2CA12 | |
| SCHEMBL29768449 | 0.86 | SLC6A4 (0.54) | HSP90AA1HTR2ASLC6A4KCNH2CA12 | |
| SCHEMBL21820786 | 0.86 | HSP90AA1 (0.71) | HSP90AA1HTR2ASLC6A4KCNH2KMO | |
| SCHEMBL11184060 | 0.83 | KDM4E (0.49) | HSP90AA1HTR2ASLC6A4KCNH2LTA4H | |
| SCHEMBL5862483 | 0.83 | HTR2A (0.54) | HSP90AA1HTR2ASLC6A4KCNH2KMO | |
| SCHEMBL257844 | 0.83 | HSP90AA1 (0.57) | HSP90AA1HTR2ASLC6A4KCNH2KMO | |
| SCHEMBL10875782 | 0.82 | SOS1 (0.58) | HTR2ASLC6A4KCNH2LTA4HCA12 | |
| SCHEMBL10614755 | 0.80 | KMO (0.62) | HSP90AA1HTR2ASLC6A4KCNH2LTA4H | |
| SCHEMBL17050939 | 0.79 | HSP90AA1 (0.53) | HSP90AA1HTR2ASLC6A4KCNH2KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118852135-A | N-acyl sulfonamide compound, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-10-29 | — | — | CN | disclosed |