Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8826213 | 0.75 | TDP1 (0.40) | TAAR1MAPTALDH1A1KDM4EGLA | |
| SCHEMBL3131842 | 0.74 | TAAR1 (0.35) | TAAR1MAPTNPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3124869 | 0.73 | TSHR (0.34) | TAAR1MAPTALDH1A1SMN1; SMN2KDM4E | |
| Butane SCHEMBL10551688 | 0.71 | CYP1A2 (0.36) | MAPTALDH1A1KDM4EGLAGAA | |
| SCHEMBL1445582 | 0.70 | HSD17B10 (0.40) | MAPTALDH1A1KDM4EGLAGAA | |
| SCHEMBL3128313 | 0.69 | KDM1A (0.33) | ALDH1A1SMN1; SMN2KDM4EGLAGAA | |
| SCHEMBL3130113 | 0.68 | HTR6 (0.34) | MAPTALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL3131793 | 0.68 | CHEK1 (0.35) | MAPTALDH1A1SMN1; SMN2KDM4EGLA | |
| SCHEMBL1685257 | 0.67 | TSHR (0.46) | MAPTCRHBPCRHR2NPSR1ALDH1A1 | |
| SCHEMBL5062914 | 0.67 | KDM4E (0.32) | ALDH1A1SMN1; SMN2KDM4EGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100204187-A1 | Purine Derivatives | PALAU PHARMA, S.A. (ES) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204187-A1 | Purine Derivatives | JAK3, JAK1, JAK2 | TAAR1 1858/4885MAPT 4689/4885CRHBP 4588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.