Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 4/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3128313 | 0.89 | KDM1A (0.33) | KDM1ATSHRKDM4ETP53SMN1; SMN2 | |
| SCHEMBL3131793 | 0.87 | CHEK1 (0.35) | KDM1AMAPTTSHRKDM4ESMN1; SMN2 | |
| SCHEMBL3131475 | 0.82 | SPAST (0.33) | CYP1A2CYP3A4CYP2D6MAPTTSHR | |
| SCHEMBL4560014 | 0.75 | PLD1 (0.46) | HTR2AKDM4ENCF1ADRB1ADRB2 | |
| SCHEMBL3120089 | 0.75 | FLT3 (0.32) | TP53ALDH1A1KMT2AMEN1 | |
| SCHEMBL2044428 | 0.72 | HRH4 (0.40) | HTR6CYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL4976430 | 0.71 | ADRB2 (0.46) | CYP1A2CYP3A4CYP2D6MAPTCYP2C19 | |
| SCHEMBL5553426 | 0.71 | HRH4 (0.44) | MAPTTSHRSMN1; SMN2NCF1ADRB1 | |
| SCHEMBL3131842 | 0.68 | TAAR1 (0.35) | MAPTKDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL3129018 | 0.68 | TAAR1 (0.35) | MAPTKDM4ESMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100204187-A1 | Purine Derivatives | PALAU PHARMA, S.A. (ES) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204187-A1 | Purine Derivatives | JAK3, JAK1, JAK2 | HTR6 1889/4885CHRNB2 4805/4885CHRNA4 4470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.