Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 5/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.38 |
| ▸ | JAK2 | O60674 | 4/20 | 0.38 |
| ▸ | JAK3 | P52333 | 4/20 | 0.38 |
| ▸ | IKBKB | O14920 | 3/20 | 0.38 |
| ▸ | JAK1 | P23458 | 2/20 | 0.38 |
| ▸ | TYK2 | P29597 | 2/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL567493 | 1.00 | IMPDH2 (0.43) | IMPDH2PIK3CACYP19A1IDO1ALDH1A1 | |
| Bromide SCHEMBL22129647 | 0.98 | IMPDH2 (0.42) | IMPDH2PIK3CACYP19A1IDO1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL22129650 | 0.98 | IMPDH2 (0.42) | IMPDH2PIK3CACYP19A1IDO1ALDH1A1 | |
| Phosphoric Acid SCHEMBL22129649 | 0.95 | IMPDH2 (0.43) | IMPDH2PIK3CAROCK2ROCK1JAK2 | |
| Sulfuric Acid SCHEMBL22129651 | 0.95 | IMPDH2 (0.43) | IMPDH2PIK3CACYP19A1ROCK2ROCK1 | |
| SCHEMBL5217117 | 0.93 | PRKCZ (0.43) | IMPDH2PIK3CACYP19A1IDO1ALDH1A1 | |
| SCHEMBL30357699 | 0.82 | LMNA (0.48) | ALDH1A1HSD17B10TDP1 | |
| SCHEMBL2263563 | 0.82 | LMNA (0.48) | ALDH1A1HSD17B10TDP1 | |
| SCHEMBL24064830 | 0.81 | IMPDH2 (0.43) | IMPDH2PIK3CACYP19A1IDO1ROCK2 | |
| SCHEMBL11146201 | 0.81 | NAPRT (0.48) | IMPDH2CYP19A1ALDH1A1HSD17B10ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3900724-B1 | ISOQUINOLINE SULFONYL CHLORIDE ACID ADDITION SALTS AND METHOD OF MANUFACTURE THEREOF | D WESTERN THERAPEUTICS INST INC (JP) | 2025-02-05 | — | — | EP | claimed |