SCHEMBL3129089

SCHEMBL3129089

O=C(O)CCNc1ccc(O)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.61
CYP1A1 P04798 2/20 0.58
ALDH1A1 P00352 4/20 0.51
KMT2A Q03164 4/20 0.51
MEN1 O00255 3/20 0.51
HSD17B10 Q99714 2/20 0.51
MAPT P10636 2/20 0.51
TSHR P16473 2/20 0.51
CASP1 P29466 1/20 0.51
HTT P42858 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
HPGD P15428 1/20 0.46
HIF1A Q16665 1/20 0.45
APP P05067 1/20 0.44
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
CA2 P00918 4/20 0.43
CAMK2A Q9UQM7 1/20 0.43
FFAR1 O14842 2/20 0.43
FFAR4 Q5NUL3 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9657820 0.86 CYP1A1 (0.53) POLBCYP1A1ALDH1A1MAPTCA2
SCHEMBL2703268 0.83 POLB (0.61) POLBALDH1A1KMT2AMEN1HSD17B10
Phenamino Methyl Acetic Acid SCHEMBL433918 0.83 POLB (0.59) POLBALDH1A1KMT2AMEN1HSD17B10
SCHEMBL3214608 0.82 POLB (0.64) POLBALDH1A1KMT2AMEN1HSD17B10
SCHEMBL3017624 0.82 POLB (0.59) POLBALDH1A1KMT2AMEN1HSD17B10
SCHEMBL23121013 0.82 POLB (0.59) POLBALDH1A1KMT2AMEN1HSD17B10
SCHEMBL9167772 0.82 POLB (0.59) POLBCYP1A1ALDH1A1KMT2AMEN1
SCHEMBL2296216 0.82 FFAR1 (0.60) POLBALDH1A1KMT2AMEN1HSD17B10
SCHEMBL12071918 0.82 POLB (0.69) POLBALDH1A1KMT2AMEN1HSD17B10
SCHEMBL1485830 0.82 POLB (0.59) POLBALDH1A1KMT2AMEN1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025108411-A1 EP300/CBP REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF 北京沐华生物科技有限责任公司 2025-05-30 WO disclosed
US-8937090-B2 Parakeratosis inhibitor, pore-shrinking agent and external composition for skin SHISEIDO COMPANY, LTD. (JP) 2015-01-20 US disclosed
CN-1993339-B Aromatic compound OTSUKA PHARMA CO LTD 2013-05-22 CN disclosed
US-20120238750-A1 AROMATIC COMPOUND OTSUKA PHARMACEUTICAL CO., LTD. 2012-09-20 US disclosed
US-20120232111-A1 Parakeratosis inhibitor, pore -shrinking agent and external compositon for skin SHISEIDO COMPANY, LTD. (JP) 2012-09-13 US disclosed
US-8236826-B2 Diarylether derivatives as antitumor agents OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2012-08-07 US disclosed
US-20120165409-A1 WRINKLE-IMPROVING AGENT SHISEIDO COMPANY, LTD. (JP) 2012-06-28 US disclosed
US-8188277-B2 Aromatic compounds for suppressing the generation of collagen OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2012-05-29 US disclosed
US-20100035881-A1 WRINKLE-IMPROVING AGENT SHISEIDO COMPANY, LTD. (JP) 2010-02-11 US disclosed
US-20100004438-A1 DIARYLETHER DERIVATIVES AS ANTITUMOR AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2010-01-07 US disclosed
EP-1941861-A1 WRINKLE-IMPROVING AGENT Shiseido Company, Limited (JP) 2008-07-09 EP disclosed
EP-1880711-A1 PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT AND EXTERNAL COMPOSITION FOR SKIN Shiseido Company, Limited (JP) 2008-01-23 EP disclosed
US-20070270422-A1 Aromatic Compounds OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-11-22 US disclosed
US-T979003-I4 Method for preparing N-(carboxyethyl-p-aminophenol MALLINCKRODT, INC. (US) 1979-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100035881-A1 WRINKLE-IMPROVING AGENT AAAS, GLA, COL14A1 POLB 1408/4885CYP1A1 4046/4885ALDH1A1 1501/4885
US-20120238750-A1 AROMATIC COMPOUND CBR1, CBR3, CYP1A1 POLB 4226/4885CYP1A1 3/4885ALDH1A1 565/4885
US-20120232111-A1 Parakeratosis inhibitor, pore -shrinking agent and external compositon for skin CUTA, AAAS, NUP160 POLB 1724/4885CYP1A1 3923/4885ALDH1A1 3543/4885
US-20100004438-A1 DIARYLETHER DERIVATIVES AS ANTITUMOR AGENTS ROS1, CBR1, CBR3 POLB 3851/4885CYP1A1 304/4885ALDH1A1 265/4885
US-20120165409-A1 WRINKLE-IMPROVING AGENT AAAS, GLA, COL14A1 POLB 882/4885CYP1A1 3677/4885ALDH1A1 1151/4885
US-20070270422-A1 Aromatic Compounds COL1A1, COL2A1, COL14A1 POLB 2808/4885CYP1A1 15/4885ALDH1A1 475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.