Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.52 |
| ▸ | AKR1B10 | O60218 | 5/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.46 |
| ▸ | TTR | P02766 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3129250 | 1.00 | ALOX5 (0.52) | ALOX5AKR1B10AKR1B1TTRCYP3A4 | |
| SCHEMBL13478915 | 0.86 | ALOX5 (0.40) | ALOX5ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL28385950 | 0.84 | ALDH1A1 (0.44) | MAPK1APPESR1KDM4EMEN1 | |
| SCHEMBL29211156 | 0.82 | ALOX5 (0.48) | ALOX5AKR1B10AKR1B1TTRCYP3A4 | |
| SCHEMBL3123681 | 0.81 | MAPT (0.50) | MAPK1KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL3123693 | 0.81 | MAPT (0.50) | MAPK1KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL873497 | 0.81 | HCAR2 (0.54) | ALOX5AKR1B10AKR1B1TTRCYP3A4 | |
| SCHEMBL872898 | 0.81 | HCAR2 (0.54) | ALOX5AKR1B10AKR1B1TTRCYP3A4 | |
| SCHEMBL872900 | 0.81 | HCAR2 (0.54) | ALOX5AKR1B10AKR1B1TTRCYP3A4 | |
| SCHEMBL3292422 | 0.78 | AKR1B10 (0.53) | ALOX5AKR1B10AKR1B1TTRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936211-B1 | Aryl-acrylic acid esters useful as precursors for organoleptic compounds | GIVAUDAN SA (CH) | 2010-07-07 | — | — | EP | claimed |
| EP-0936211-B1 | Aryl-acrylic acid esters useful as precursors for organoleptic compounds | GIVAUDAN SA (CH) | 2010-07-07 | — | — | EP | disclosed |
| US-6096918-A | USEFUL FOR THE DELIVERY OF ORGANOLEPTIC COMPOUNDS, ESPECIALLY FOR FLAVORS, FRAGRANCES, MASKING AGENTS AND ANTIMICROBIAL COMPOUNDS. THEY CAN ALSO DELIVER FLUORESCENT WHITENING AGENTS. | GIVAUDAN ROURE (INTERNATIONAL) SA (CH) | 2000-08-01 | — | — | US | disclosed |
| EP-0936211-A2 | Aryl-acrylic acid esters useful as precursors for organoleptic compounds | Givaudan Roure (International) S.A. (CH) | 1999-08-18 | — | — | EP | disclosed |