Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3122088 | 0.92 | FKBP1A (0.51) | LMNAFKBP1AALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL3129280 | 0.78 | ALDH1A1 (0.48) | LMNAFKBP1AALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL996592 | 0.78 | NPC1 (0.53) | LMNAALDH1A1SMN1; SMN2RAB9AUSP2 | |
| SCHEMBL3130513 | 0.76 | USP2 (0.56) | LMNAFKBP1ASMN1; SMN2RAB9AUSP2 | |
| SCHEMBL964201 | 0.74 | CYP2C9 (0.60) | LMNAALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL3757565 | 0.72 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL3119026 | 0.72 | GAA (0.55) | LMNAFKBP1AALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL7427604 | 0.72 | MAPT (0.55) | FKBP1AALDH1A1SMN1; SMN2RAB9AUSP2 | |
| SCHEMBL3121594 | 0.70 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL7068444 | 0.70 | FKBP1A (0.82) | LMNAFKBP1AALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | disclosed |