Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.38 |
| ▸ | EPHA2 | P29317 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | YAP1 | P46937 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31293172 | 0.90 | USP30 (0.41) | USP30JAK2JAK1GPR119SMN1; SMN2 | |
| SCHEMBL31293104 | 0.89 | EPHA2 (0.42) | USP30JAK2JAK1GPR119EPHA2 | |
| SCHEMBL31292840 | 0.87 | USP30 (0.51) | USP30JAK2JAK1GPR119EPHA2 | |
| SCHEMBL31293161 | 0.85 | ALDH1A1 (0.40) | USP30JAK2JAK1GPR119SMN1; SMN2 | |
| SCHEMBL29440526 | 0.83 | GPR119 (0.47) | USP30JAK2JAK1NR1H2GPR119 | |
| SCHEMBL22765085 | 0.83 | GPR119 (0.47) | USP30JAK2JAK1NR1H2GPR119 | |
| SCHEMBL28686452 | 0.83 | GPR119 (0.47) | USP30JAK2JAK1NR1H2GPR119 | |
| SCHEMBL31291044 | 0.83 | GPR119 (0.47) | USP30JAK2JAK1NR1H2GPR119 | |
| SCHEMBL25957593 | 0.83 | GPR119 (0.47) | USP30JAK2JAK1NR1H2GPR119 | |
| SCHEMBL31293276 | 0.83 | USP30 (0.42) | USP30JAK2JAK1NR1H2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747236-A1 | PIPERIDINE, MORPHOLINE AND TETRAHYDRO-PYRIDAZINE COMPOUNDS WITH LP(A) LOWERING ACTIVITY | Eli Lilly and Company (US) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025024210-A1 | PIPERIDINE, MORPHOLINE AND TETRAHYDRO-PYRIDAZINE COMPOUNDS WITH LP(A) LOWERING ACTIVITY | ELI LILLY AND COMPANY (US) | 2025-01-30 | — | — | WO | disclosed |