Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31293172 | 0.89 | USP30 (0.41) | USP30JAK2JAK1GPR119 | |
| SCHEMBL31292816 | 0.87 | USP30 (0.40) | USP30JAK2JAK1EPHA2GPR119 | |
| SCHEMBL31293104 | 0.87 | EPHA2 (0.42) | USP30JAK2JAK1EPHA2GPR119 | |
| SCHEMBL30543854 | 0.84 | USP30 (0.56) | USP30EPHX2JAK2JAK1GPR119 | |
| SCHEMBL25957771 | 0.84 | USP30 (0.56) | USP30EPHX2JAK2JAK1GPR119 | |
| SCHEMBL31599077 | 0.84 | USP30 (0.56) | USP30EPHX2JAK2JAK1GPR119 | |
| SCHEMBL31293161 | 0.84 | ALDH1A1 (0.40) | USP30JAK2JAK1GPR119 | |
| SCHEMBL31293276 | 0.82 | USP30 (0.42) | USP30JAK2JAK1EPHA2GPR119 | |
| SCHEMBL31292798 | 0.80 | JAK2 (0.47) | USP30JAK2JAK1GPR119 | |
| SCHEMBL31293063 | 0.80 | JAK2 (0.48) | USP30JAK2JAK1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747236-A1 | PIPERIDINE, MORPHOLINE AND TETRAHYDRO-PYRIDAZINE COMPOUNDS WITH LP(A) LOWERING ACTIVITY | Eli Lilly and Company (US) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025024210-A1 | PIPERIDINE, MORPHOLINE AND TETRAHYDRO-PYRIDAZINE COMPOUNDS WITH LP(A) LOWERING ACTIVITY | ELI LILLY AND COMPANY (US) | 2025-01-30 | — | — | WO | disclosed |