Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 1/20 | 0.53 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3129302 | 1.00 | SLC5A1 (0.53) | SLC5A1SLC5A2CYP2C19CYP19A1CYP2C9 | |
| SCHEMBL30335008 | 0.76 | MAPT (0.58) | SLC5A1SLC5A2CYP2C19CYP19A1CYP2C9 | |
| SCHEMBL12599524 | 0.76 | MAPT (0.58) | SLC5A1SLC5A2CYP2C19CYP19A1CYP2C9 | |
| 2',4',6-Trihydroxychalcone SCHEMBL675431 | 0.71 | SLC5A1 (1.00) | SLC5A1SLC5A2CYP2C19CYP19A1CYP2C9 | |
| 2',4',6-Trihydroxychalcone SCHEMBL675432 | 0.71 | SLC5A1 (1.00) | SLC5A1SLC5A2CYP2C19CYP19A1CYP2C9 | |
| SCHEMBL25234449 | 0.68 | SLC5A1 (0.76) | SLC5A1SLC5A2CYP2C19CYP19A1CYP2C9 | |
| SCHEMBL17483792 | 0.68 | SLC5A1 (0.76) | SLC5A1SLC5A2CYP2C19CYP19A1CYP2C9 | |
| SCHEMBL12599532 | 0.68 | NFKB1 (0.50) | SLC5A1SLC5A2CYP2C19CYP19A1CYP2C9 | |
| SCHEMBL15575116 | 0.68 | SLC5A1 (0.65) | SLC5A1SLC5A2CYP2C19CYP19A1CYP2C9 | |
| SCHEMBL15575117 | 0.68 | SLC5A1 (0.65) | SLC5A1SLC5A2CYP2C19CYP19A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2010043061-A | ANTI-HELICOBACTER PYLORI AGENT | TOYAMA UNIV | 2010-02-25 | — | — | JP | disclosed |