Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 6/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31293564 | 0.87 | GRM7 (0.37) | GRM7EPHX2MEN1KMT2AEPHX1 | |
| SCHEMBL31293848 | 0.86 | IRAK4 (0.48) | GRM7EPHX2MEN1KMT2AEPHX1 | |
| SCHEMBL31293631 | 0.85 | EPHX2 (0.43) | EPHX2EPHX1 | |
| SCHEMBL31293937 | 0.85 | IRAK4 (0.48) | IRAK4 | |
| SCHEMBL31293918 | 0.84 | KDR (0.36) | EPHX2 | |
| SCHEMBL31293619 | 0.83 | CHEK1 (0.36) | GRM7EPHX2EPHX1IRAK4 | |
| SCHEMBL31293884 | 0.81 | MEN1 (0.37) | GRM7EPHX2MEN1KMT2AEPHX1 | |
| SCHEMBL31293917 | 0.81 | ROCK2 (0.33) | EPHX2CYP3A4 | |
| SCHEMBL31293519 | 0.80 | RAB9A (0.46) | EPHX2MEN1KMT2A | |
| SCHEMBL31293525 | 0.79 | MAPT (0.36) | MEN1KMT2AIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724439-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2026-04-15 | — | — | EP | claimed |
| WO-2024251855-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-12-12 | — | — | WO | claimed |