Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 6/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31293631 | 0.90 | EPHX2 (0.43) | EPHX2CCKBRCXCR3 | |
| SCHEMBL31293858 | 0.88 | KMT2A (0.43) | RAB9ANPC1MEN1MAPTKMT2A | |
| SCHEMBL31293875 | 0.85 | EPHX2 (0.46) | MEN1MAPTKMT2AEPHX2ALDH1A1 | |
| SCHEMBL31293436 | 0.83 | UBE2M (0.35) | MEN1KMT2AEPHX2ALDH1A1SMN1; SMN2 | |
| SCHEMBL31293678 | 0.80 | ADORA3 (0.33) | EPHX2SMN1; SMN2TP53CXCR3 | |
| SCHEMBL31293522 | 0.80 | GRM7 (0.36) | MEN1KMT2AEPHX2 | |
| SCHEMBL31293851 | 0.78 | SCN10A (0.35) | MEN1KMT2AEPHX2CXCR3 | |
| SCHEMBL31293675 | 0.78 | CDK8 (0.43) | EPHX2CCNCCDK8 | |
| SCHEMBL31293924 | 0.76 | EPHX2 (0.41) | RAB9ANPC1MEN1KMT2AEPHX2 | |
| SCHEMBL31293554 | 0.76 | SPR (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724439-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2026-04-15 | — | — | EP | claimed |
| WO-2024251855-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-12-12 | — | — | WO | claimed |