Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31293787 | 0.84 | EPHX2 (0.57) | MEN1KMT2AMAPTXBP1ALDH1A1 | |
| SCHEMBL20983843 | 0.84 | ABHD6 (0.47) | SMN1; SMN2KMT2AMAPTRXFP1ABHD6 | |
| SCHEMBL31293771 | 0.82 | DCUN1D1 (0.47) | RXFP1POLB | |
| SCHEMBL31294047 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2MEN1KMT2AMAPTGAA | |
| SCHEMBL31294042 | 0.77 | GRIN2B (0.51) | SMN1; SMN2MEN1KMT2AMAPTGAA | |
| SCHEMBL20983865 | 0.76 | ABHD6 (0.72) | MEN1KMT2AABHD6MGLLEPHX2 | |
| SCHEMBL6863428 | 0.76 | TACR1 (0.48) | MAPTALDH1A1 | |
| SCHEMBL32660716 | 0.76 | MAPT (0.69) | SMN1; SMN2MEN1KMT2AMAPTGAA | |
| SCHEMBL18658290 | 0.75 | UBE2M (0.67) | SMN1; SMN2MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL29491079 | 0.75 | UBE2M (0.67) | SMN1; SMN2MEN1KMT2AMAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724439-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2026-04-15 | — | — | EP | disclosed |
| WO-2024251855-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-12-12 | — | — | WO | disclosed |