Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 5/20 | 0.57 |
| ▸ | LOX | P28300 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.57 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.37 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | MGMT | P16455 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25388344 | 0.82 | LOXL2 (0.50) | LOXL2LOXRECQLLOXL3GRM5 | |
| SCHEMBL12017629 | 0.80 | LOX (0.57) | LOXL2LOXRECQLLOXL3GRM5 | |
| SCHEMBL15153914 | 0.78 | FDPS (0.51) | LOXL2LOXRECQLLOXL3GRM5 | |
| SCHEMBL26984227 | 0.76 | LOXL2 (0.39) | LOXL2LOXRECQLLOXL3IDO1 | |
| SCHEMBL31293809 | 0.76 | NOS3 (0.57) | LOXL2LOXLOXL3IGF1R | |
| SCHEMBL30319464 | 0.76 | RECQL (0.41) | LOXL2LOXRECQLLOXL3GRM5 | |
| SCHEMBL25129859 | 0.75 | RECQL (0.40) | LOXL2LOXRECQLLOXL3GRM5 | |
| SCHEMBL31047312 | 0.74 | S1PR2 (0.31) | LOXL2LOXRECQLLOXL3 | |
| SCHEMBL1503624 | 0.74 | — | — | |
| SCHEMBL4438687 | 0.73 | RECQL (0.59) | LOXL2LOXRECQLLOXL3GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724439-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2026-04-15 | — | — | EP | disclosed |
| WO-2024251855-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-12-12 | — | — | WO | disclosed |