Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.48 |
| ▸ | DCUN1D1 | Q96GG9 | 11/20 | 0.45 |
| ▸ | UBE2M | P61081 | 9/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CCKBR | P32239 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31293582 | 0.94 | EPHX2 (0.41) | EPHX2DCUN1D1UBE2MMEN1KMT2A | |
| SCHEMBL31293823 | 0.91 | DCUN1D1 (0.50) | EPHX2DCUN1D1UBE2MMEN1KMT2A | |
| SCHEMBL31293571 | 0.89 | EPHX2 (0.35) | EPHX2DCUN1D1UBE2MMEN1KMT2A | |
| SCHEMBL31293831 | 0.89 | USP2 (0.44) | EPHX2MEN1KMT2ACCKBRMAPT | |
| SCHEMBL31293752 | 0.89 | EPHX2 (0.44) | EPHX2DCUN1D1UBE2MMEN1KMT2A | |
| SCHEMBL31293599 | 0.89 | CXCR3 (0.40) | EPHX2 | |
| SCHEMBL31293540 | 0.88 | EPHX2 (0.45) | EPHX2DCUN1D1UBE2MMEN1KMT2A | |
| SCHEMBL31294025 | 0.88 | SMN1; SMN2 (0.36) | EPHX2DCUN1D1UBE2MMEN1KMT2A | |
| SCHEMBL31293745 | 0.88 | UBE2M (0.44) | EPHX2DCUN1D1UBE2MMEN1KMT2A | |
| SCHEMBL31293632 | 0.87 | SMARCA2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724439-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2026-04-15 | — | — | EP | claimed |
| WO-2024251855-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-12-12 | — | — | WO | claimed |