SCHEMBL31293632

SCHEMBL31293632

Cn1ccn2ncc(C(=O)N3CC4(CC(NC(=O)Nc5ccnc(C(F)(F)F)c5)C4)C3)c12

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SMARCA2 P51531 1/20 0.39
SMARCA4 P51532 1/20 0.39
MALT1 Q9UDY8 17/20 0.39
KDR P35968 1/20 0.36
BIRC3 Q13489 1/20 0.35
SPR P35270 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31293483 0.88 SYK (0.35)
SCHEMBL31293682 0.88 EPHX2 (0.31)
SCHEMBL31293845 0.87 EPHX2 (0.48)
SCHEMBL31293650 0.86 SYK (0.41) KDR
SCHEMBL31293490 0.86 EPHX2 (0.40) KDR
SCHEMBL31293908 0.86 WNT1 (0.33) KDR
SCHEMBL31293401 0.86 EPHX2 (0.47) KDR
SCHEMBL31293618 0.85 MALT1 (0.35) MALT1
SCHEMBL31293571 0.85 EPHX2 (0.35) MALT1KDRBIRC3
SCHEMBL31293831 0.84 USP2 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724439-A1 HETEROARYL DERIVATIVES AS DDRS INHIBITORS Chiesi Farmaceutici S.p.A. (IT) 2026-04-15 EP disclosed
WO-2024251855-A1 HETEROARYL DERIVATIVES AS DDRS INHIBITORS CHIESI FARMACEUTICI S.P.A. (IT) 2024-12-12 WO disclosed