Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.43 |
| ▸ | CFTR | P13569 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16031477 | 0.76 | MEN1 (0.44) | NOTUMKDM4EALDH1A1GAATDP1 | |
| SCHEMBL2446096 | 0.75 | DAPK3 (0.41) | CFTRKDM4EALDH1A1GAATDP1 | |
| SCHEMBL16032673 | 0.74 | FFAR4 (0.44) | NOTUMKDM4EALDH1A1GAAPOLB | |
| SCHEMBL4247977 | 0.74 | ABL1 (0.40) | CFTRKDM4EALDH1A1GAAPOLB | |
| SCHEMBL13731286 | 0.74 | DAPK3 (0.40) | NOTUMCFTRKDM4EALDH1A1TDP1 | |
| SCHEMBL27077836 | 0.73 | NOTUM (0.38) | NOTUMCFTRKDM4EALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL1396143 | 0.72 | ABL1 (0.39) | CFTRKDM4EALDH1A1GAAPOLB | |
| SCHEMBL20101952 | 0.71 | ALDH1A1 (0.40) | CFTRKDM4EALDH1A1GAATDP1 | |
| Ethane SCHEMBL15559374 | 0.71 | ABL1 (0.38) | NOTUMCFTRKDM4EALDH1A1GAA | |
| SCHEMBL13505506 | 0.71 | GAA (0.49) | KDM4EALDH1A1GAAPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747256-A1 | PARP1 INHIBITOR COMPOUNDS | Duke Street Bio Limited (GB) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025073583-A1 | PARP1 INHIBITOR COMPOUNDS | Duke Street Bio Limited (GB) | 2025-04-10 | — | — | WO | disclosed |
| WO-2025026745-A1 | PARP1 INHIBITOR COMPOUNDS | Duke Street Bio Limited (GB) | 2025-02-06 | — | — | WO | disclosed |