SCHEMBL31294583

SCHEMBL31294583

CCOC(=O)CC(C)c1ccc(F)cc1F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.43
MAPT P10636 4/20 0.42
RAB9A P51151 2/20 0.42
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
LMNA P02545 2/20 0.40
MEN1 O00255 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
KMT2A Q03164 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
ALDH1A1 P00352 3/20 0.40
IDO1 P14902 1/20 0.39
TDO2 P48775 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
TSHR P16473 1/20 0.38
NPC1 O15118 1/20 0.38
KAT6A Q92794 2/20 0.37
PKM P14618 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12603183 0.86 APLNR (0.41) POLBMAPTRAB9ALMNAMEN1
SCHEMBL8246743 0.86 APLNR (0.42) MAPTLMNAMEN1KMT2ANPSR1
SCHEMBL3384367 0.85 IDO1 (0.42) POLBMAPTRAB9ACES2CES1
SCHEMBL11546401 0.80 PPARA (0.39) RAB9ACYP1A2TSHRNPC1
SCHEMBL11540691 0.79 CYP2C19 (0.46) POLBMAPTRAB9ALMNAMEN1
SCHEMBL13318198 0.79 GPBAR1 (0.40) POLBMAPTRAB9AKMT2ANPSR1
SCHEMBL9366709 0.78 MAPT (0.49) POLBMAPTRAB9ACES2CES1
SCHEMBL9160661 0.78 CES2 (0.45) CES2CES1ALDH1A1IDO1TDO2
SCHEMBL3390348 0.78 NPSR1 (0.48) POLBMAPTLMNAMEN1CYP1A2
SCHEMBL11543137 0.78 FFAR1 (0.46) POLBLMNAMEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735423-A1 KV7 MODULATORS Saniona A/S (DK) 2026-05-06 EP disclosed
WO-2025003343-A1 KV7 MODULATORS SANIONA A/S (DK) 2025-01-02 WO disclosed