SCHEMBL10893299

SCHEMBL10893299

CCC(C)c1cc(Sc2cc(C(C)C)c(O)c(C(C)CC)c2)cc(C(C)C)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
GABRA1 P14867 6/20 0.44
GABRB1 P18505 5/20 0.44
GABRB2 P47870 3/20 0.44
GSR P00390 1/20 0.42
TSHR P16473 2/20 0.41
RORC P51449 1/20 0.39
GAA P10253 3/20 0.38
HPGD P15428 2/20 0.38
FAAH O00519 1/20 0.38
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
GABRG2 P18507 1/20 0.38
PTGS1 P23219 1/20 0.38
SLC6A2 P23975 1/20 0.38
HTR2C P28335 1/20 0.38
GABRB3 P28472 1/20 0.38
GABRA5 P31644 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3129487 0.94 TSHR (0.45) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL9701896 0.86 CA1 (0.61) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL13779538 0.82 CA1 (0.71) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL4549116 0.81 CA1 (0.50) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL11795634 0.80 TSHR (0.37) TSHRRORCGAAHPGDCYP3A4
SCHEMBL11803509 0.80 TSHR (0.37) TSHRRORCGAALMNAALDH1A1
SCHEMBL9418462 0.79 CA1 (0.34) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL10894340 0.78 CA1 (0.42) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL203191 0.76 RORC (0.45) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL10138485 0.76 CA1 (0.54) CA1CA2GABRA1GABRB1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4626259-A ADDITIVE OF ORGANIC NITRATE IGNITION ACCELERATOR AND 4,4'-THIOBISPHENOLS; REDUCED COKING OF INJECTOR NOZZLES ETHYL CORPORATION (US) 1986-12-02 US claimed
US-4626259-A ADDITIVE OF ORGANIC NITRATE IGNITION ACCELERATOR AND 4,4'-THIOBISPHENOLS; REDUCED COKING OF INJECTOR NOZZLES ETHYL CORPORATION (US) 1986-12-02 US disclosed