Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31295205 | 0.82 | CYP2D6 (0.49) | SIGMAR1KCNH2HTR1AADRA1D | |
| SCHEMBL31295164 | 0.76 | SSTR4 (0.41) | SIGMAR1KCNH2DRD2HTR2BHTR1A | |
| SCHEMBL31295104 | 0.74 | CNR2 (0.48) | DRD2DRD4ACHE | |
| SCHEMBL31295077 | 0.71 | CYP2D6 (0.58) | HTR1AADRA1D | |
| SCHEMBL23926367 | 0.71 | SIGMAR1 (0.65) | SIGMAR1KCNH2DRD2HTR2BHRH3 | |
| SCHEMBL30118922 | 0.71 | SIGMAR1 (0.65) | SIGMAR1KCNH2DRD2HTR2BHRH3 | |
| SCHEMBL31295196 | 0.68 | HTR1A (0.50) | HTR1AADRA1D | |
| SCHEMBL7923985 | 0.67 | HRH3 (0.82) | SIGMAR1KCNH2DRD2HTR2BHRH3 | |
| SCHEMBL31295194 | 0.66 | HTR1A (0.43) | SIGMAR1KCNH2DRD2HTR1ADRD4 | |
| SCHEMBL9644974 | 0.66 | SIGMAR1 (0.65) | SIGMAR1KCNH2DRD2HTR2BHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119698412-A | 5-HT2A receptor agonist, and preparation method and application thereof | 上海翊石医药科技有限公司 | 2025-03-25 | — | — | CN | disclosed |
| WO-2025021120-A1 | 5-HT2A RECEPTOR AGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊石医药科技有限公司 | 2025-01-30 | — | — | WO | disclosed |