SCHEMBL31295745

SCHEMBL31295745

N#Cc1cccc2c(-c3ccccc3)cccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.50
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CYP1A2 P05177 3/20 0.45
CYP2C9 P11712 3/20 0.45
CYP2C19 P33261 3/20 0.45
ALDH1A1 P00352 2/20 0.45
NPSR1 Q6W5P4 1/20 0.45
KDM4E B2RXH2 1/20 0.45
GALR3 O60755 1/20 0.45
GAA P10253 1/20 0.45
HPGD P15428 1/20 0.45
IMPDH2 P12268 1/20 0.44
IMPDH1 P20839 1/20 0.44
MCL1 Q07820 1/20 0.44
GABRG2 P18507 1/20 0.44
GABRB3 P28472 1/20 0.44
GABRA5 P31644 1/20 0.44
GABRA3 P34903 1/20 0.44
USP8 P40818 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2350899 0.89 IMPDH2 (0.50) ESR2CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL23624362 0.82 ESR2 (0.46) ESR2ALDH1A1KDM4EMCL1LRRK2
SCHEMBL23624588 0.82 ESR2 (0.46) ESR2CA1CA2CYP1A2CYP2C9
SCHEMBL223 0.82 ESR2 (0.69) ESR2CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL29662886 0.82 ESR2 (0.69) ESR2CYP1A2CYP2C9CYP2C19ALDH1A1
Water SCHEMBL3178714 0.82 ESR2 (0.69) ESR2CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL27895577 0.82 ESR2 (0.69) ESR2CA1CA2CYP1A2CYP2C9
SCHEMBL11228244 0.82 IMPDH2 (0.59) CA1CA2ALDH1A1KDM4EGAA
SCHEMBL24067859 0.82 ESR2 (0.39) ESR2CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL45954 0.82 CA1 (0.54) CA1CA2ALDH1A1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119219454-A Method for preparing aromatic nitrile compound by photoinitiating nitroarene denitration cyanation 武汉光化学技术研究院 2024-12-31 CN disclosed