Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21851374 | 0.73 | VRK1 (0.41) | LMNAKDM4ERECQLMEN1KMT2A | |
| SCHEMBL9951754 | 0.72 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2KDM4EHCAR2KMO | |
| SCHEMBL24257783 | 0.72 | EGLN1 (0.44) | ALDH1A1RNASEH1 | |
| SCHEMBL30453338 | 0.72 | EGLN1 (0.44) | ALDH1A1RNASEH1 | |
| SCHEMBL1795934 | 0.68 | SMN1; SMN2 (0.41) | ALDH1A1MAPK1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL25037125 | 0.68 | TSHR (0.45) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL4769713 | 0.67 | GRM5 (0.36) | ALDH1A1MAPK1SMN1; SMN2KMOKMT2A | |
| SCHEMBL31214055 | 0.67 | ASPH (0.41) | ALDH1A1MAPK1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL22866606 | 0.67 | ALDH1A1 (0.48) | ALDH1A1MAPK1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL15058237 | 0.67 | SMN1; SMN2 (0.48) | ALDH1A1MAPK1SMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735447-A1 | AROMATIC NITROGEN-CONTAINING COMPOUNDS, PREPARATION METHODS AND MEDICINAL USES THEREOF | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025002413-A1 | AROMATIC NITROGEN-CONTAINING COMPOUNDS, PREPARATION METHODS AND MEDICINAL USES THEREOF | SHANGHAI HANSOH BIOMEDICAL CO., LTD. (CN) | 2025-01-02 | — | — | WO | disclosed |