Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | RNASEH1 | O60930 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24257783 | 1.00 | EGLN1 (0.44) | EGLN1ALDH1A1CNR2GPR55RNASEH1 | |
| SCHEMBL30452522 | 0.85 | RNASEH1 (0.45) | EGLN1ALDH1A1CNR2GPR55RNASEH1 | |
| SCHEMBL24257546 | 0.85 | RNASEH1 (0.45) | EGLN1ALDH1A1CNR2GPR55RNASEH1 | |
| SCHEMBL24257458 | 0.84 | EGLN1 (0.67) | EGLN1ALDH1A1 | |
| SCHEMBL24257549 | 0.83 | EGLN1 (0.51) | EGLN1ALDH1A1CNR2GPR55HTT | |
| Formic Acid SCHEMBL30453300 | 0.80 | EGLN1 (0.62) | EGLN1ALDH1A1 | |
| SCHEMBL30452505 | 0.78 | EGLN1 (0.51) | EGLN1ALDH1A1 | |
| SCHEMBL26260056 | 0.78 | EGLN1 (0.51) | EGLN1ALDH1A1 | |
| SCHEMBL31295859 | 0.72 | ALDH1A1 (0.39) | ALDH1A1RNASEH1 | |
| SCHEMBL754062 | 0.71 | NPSR1 (0.41) | EGLN1ALDH1A1CNR2GPR55HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116670131-A | PHD inhibitor compounds, compositions, and methods of use | 阿克比治疗有限公司 | 2023-08-29 | — | — | CN | disclosed |
| EP-4196466-A1 | PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | Akebia Therapeutics Inc. (US) | 2023-06-21 | — | — | EP | disclosed |